This seminar organized by the Central African Network on Clinical Trials (CANTAM) in collaboration with the Congolese Foundation for Medical Research (FCRM) and under the patronage of the Ministry of Health and Population of Republic of Congo, brought together participants from the sub region (Cameroon, Gabon, Congo, DRC, and Chad) in their diverse qualities (members of the Ethic committee, Malaria Researchers, Managers of Malaria Control Programs…) and facilitators from the National Institute of Health and Medical research in France, Prof Hervé Chneiweiss president of the Ethics Committee of INSERM and his general secretory, Dr. Francois Hirsch